Lab Test Image

DUTCH Complete Plus + CAR

£399.00

Category:

Description

DUTCH Complete Plus offers a thorough assessment of 35 sex and adrenal hormones, including their metabolites, providing insights into hormonal balance. It analyzes the pattern of free cortisol and cortisone, emphasising the Cortisol Awakening Response to test your adrenal function. Additionally, it measures 8-OHdG, melatonin, and nine organic acids, including markers for B vitamins, glutathione, dopamine, and neuroinflammation.
Includes full written report, nutrition, lifestyle and supplement recommendations to go ahead and implement after having a 30 minute consultation with Ollie.
Sample type:
Dried Urine & Saliva
Biomarkers tested:
43
Lab Processing time:
7-10 Business days (excludes transit)
Tested Biomarkers:
  • 2-Methoxy-E1
  • 2-OH-E1
  • 2-OH-E2
  • 4-OH-E1
  • 4-OH-E2
  • 5-Hydroxyindolacetate (5HIAA)
  • 5a-Androstanediol
  • 5a-Dihydrotestosterone (5a-DHT)
  • 5b-Androstanediol
  • 8-hydroxy-2′-deoxyguanosine (8-OHdG)
  • 16-OH-E1
  • 24hr Free Cortisol
  • 24hr Free Cortisone
  • 𝛼-Pregnanediol
  • 𝛼-Tetrahydrocortisol (a-THF)
  • Androsterone
  • β-Hydroxyisovalerate
  • β-Pregnanediol
  • β-Tetrahydrocortisone (b-THE)
  • β-Tetrahyrodcortisol (b-THF)
  • Cortisol (Saliva)
  • Cortisone (Saliva)
  • Dehydroepiandrosterone Sulfate (DHEA-S)
  • Dihydrotestosterone (DHT)
  • Epi-Testosterone
  • Estradiol (E2)
  • Estriol (E3)
  • Estrone (E1)
  • Etiocholanolone
  • Homogentisic Homovanillic Acid (HVA)
  • Indican
  • Melatonin
  • Metabolized cortisol (THF+THE)
  • Methylation activity (2-Me-E1 / 2-OH-E1)
  • Methylmalonic Acid (MMA)
  • Progesterone (Pg) (calculated equivalent)
  • Pyroglutamate
  • Quinolinate (Neuroinflammation marker)
  • Testosterone
  • Total Dehydroepiandrosterone (DHEA)
  • Total Oestrogen (Estrogen)
  • Vanillmandelic Acid (VMA)
  • Xanthurenate
Methodology:

Gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) are advanced analytical techniques for separating, identifying, and quantifying complex mixtures of substances. Cortisol, cortisone, 8-OHdG, melatonin (6-OHMS), organic acid tests and metabolites related to cortisol are tested by LC-MS/MS. This combines liquid chromatography’s separation capabilities with tandem mass spectrometry’s sensitivity and specificity. Compounds are separated by liquid chromatography and then analyzed in tandem mass spectrometers, where they are ionized, fragmented, and selectively isolated for precise identification and quantification. The remaining hormones are tested by GC-MS. This utilises gas chromatography to separate compounds based on their affinity for a column and their boiling points, followed by mass spectrometry to ionize and analyze the compounds based on their mass-to-charge ratios.

When should you consider this test?
Consider DUTCH Plus for a comprehensive assessment of sex hormone and adrenal imbalances in both genders. It includes the Cortisol Awakening Response (CAR), providing a unique insight into HPA axis function. This test combines dried urine and saliva for easy sample collection and offers detailed insights with markers for nutritional, detoxification, neurotransmitter organic acids, melatonin, and oxidative stress. Ideal for guiding personalized therapeutic recommendations.
Tests can be refunded within 14 days of order providing kit is in an unopened condition and can be returned to the lab.

Related products